Table 2 Other potential epithelial stem cells
From: Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
Cell type | Marker genes | Differentiation potential | Hallmarks |
|---|---|---|---|
Variant Club Cells | Scgb1a1+, Cyp2f2− | Club, Ciliated | Located near NEBs |
| Â | Â | Ciliated | Survive Naphthalene injury |
Broncho-Alveolar Stem Cells | Scgb1a1+, Sftpc+ | AT-II, Ciliated | Wnt signaling induces proliferation BASC [168] |
| Â | Â | Â | Located at BADJ |
Itgα6+, Itgβ4+Alveolar progenitor | Scgb1a1−, Sftpc−, Itgα6+, Itgβ4+ | AT-II, Club | Located at BADJ and Alveolar wall |
AT-II | Sftpc+, LysM | Sca1+, Sftpc+ AT-I progenitor cell | EGF induced proliferation [37] |
| Â | Â | AT-I | Wnt dependent conversion to AT-I [41] |