Fig. 3
From: Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
Example of a human breathing lung-on-a-chip microdevice. Lung-on-a-chip microfluidic device with compartmentalized microchannels to mimic a breathing lung (From Huh et al., “Reconstituting organ-level lung functions on a chip”, Science 2010; 328:1662–8. Reprinted with permission from the AAAS [100]). See original reference for detailed description of the figure. In brief, (a) indicates the creation of mechanical breathing movements causing mechanical stretch of the membrane, (b) shows the physiology of the normal breathing human lung, (c) and (d) show the assembly and etching of the microdevice, and (e) visualizes the actual size of the device