Fig. 1

Inflammation in BLM-treated mice a The body weight changes of BLM-treated mice and control mice over time (n = 10 each). *p < 0.05. b The results of an analysis of the total cell numbers and cell types in the bronchoalveolar lavage fluid (BALF) (n = 10 each). *p < 0.05. c The expression levels of MCP-1, TGF-β and COL1A1 mRNA were increased in the lungs from the BLM-treated mice compared to the control mice (n = 6 each). *p < 0.05. d The Ashcroft score in the BLM-treated mice was significantly increased compared to that of the control mice (n = 4 each). *p < 0.05. e Representative photomicrographs of lung tissue sections stained with H&E, Masson’s trichrome or with an anti-α-SMA antibody. All results are expressed as the means ± SEM