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Table 3 Expression of TLRs 2 and 4 distributed as per total serum IgE

From: Expression of toll-like receptors 2 and 4 in subjects with asthma by total serum IgE level

 

Normal total serum IgE (n = 29)

High total serum IgE (n = 15)

P

Percentage of cells expressing TLR2

   

Neutrophils (sputum)

   

Cells (%)

0.89 (0.97)

2.81 (5.02)

0.180

MFI

2.78 (2.24)

2.81 (1.26)

0.954

Macrophages (sputum)

   

Cells (%)

30.78 (21.91)

31.7 (26.36)

0.907

MFI

2.18 (0.42)

2.55 (0.73)

0.103

Neutrophils (blood)

   

Cells (%)

1.19 (0.51)

1.36 (1.32)

0.637

MFI

1.77 (0.68)

1.77 (0.64)

0.974

Monocytes (blood)

   

Cells (%)

85.54 (10.42)

82.61 (15.14)

0.510

MFI

2.47 (0.59)

2.71 (0.98)

0.379

Percentage of cells expressing TLR4

   

Neutrophils (sputum)

   

Cells (%)

2.96 (2.7)

7.64 (11.08)

0.118

MFI

3.83 (2.91)

4.9 (5.34)

0.157

Macrophages (sputum)

   

Cells (%)

28.84 (15.16)

42.99 (22.49)

0.048

MFI

13.18 (11.41)

13.13 (14.39)

0.990

Neutrophils (blood)

   

Cells (%)

2.13 (2.12)

1.74 (1.55)

0.532

MFI

2.66 (1.41)

2.51 (0.72)

0.576

Monocytes (blood)

   

Cells (%)

61.81 (14.42)

65.41 (17.00)

0.468

MFI

2.89 (0.93)

2.56 (0.97)

0.281

  1. MFI Mean of Fluorescence Intensity, TLR toll-like receptors. Values are mean percentage and standard deviation (STD) for cell counts, and mean (STD) for MFI