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Table 1 Interleukin-26 in the airways of children with uncontrolled versus controlled asthma

From: The cytokine interleukin-26 as a biomarker in pediatric asthma

 

IL-26 (ng/ml) Uncontrolled asthma

n

IL-26 (ng/ml) Controlled asthma

n

p-value*

All patients

4.4 (1.9–14)

48

2.4 (1.3–4.5)

28

0.077

Low B-EOS (≤ 0.3×109/L)

4.6 (2.3–13)

27

2.3 (1.3–4.5)

22

0.038*

High B-EOS (>0.3×109/L)

4.1 (1.7–16)

21

2.9 (1–31)

5

0.61

Low FENO (≤18.3 p.p.b.)

4.1 (2.2–16)

23

2.0 (1.2–3.6)

13

0.055

High FENO (>18.3 p.p.b)

5.0 (1.8–13)

25

2.7 (1.4–24)

15

0.54

  1. Footnotes. The IL-26 concentrations are presented as medians with inter-quartile ranges
  2. The median values in the entire cohort of the respective biomarker were used to define the cut-off between high and low levels of the various biomarkers. B-EOS blood eosinophils, FENO the fraction of nitric oxide in exhaled air, in parts per billion. *Independent samples, analyzed by Mann–Whitney U-test (SPSS® version 20)