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Table 1 Characteristics Of Subjects

From: Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity

 

Healthy volunteers (n = 8)

Severe asthmatics (n = 10)

Gender (M:F)

2:6

4:6

Age

49.9 ± 3.2

53.2 ± 4.9

FEV1.0 %pred.

90.7 ± 3.5

71.7 ± 5.6

FEV1.0/FVC

78.1 ± 1.5

69.1 ± 2.5

ICS

none

10/10

(mean dose)

 

a640 ± 72 μg

Oral prednisolone

none

6/10

(mean dose)

 

10.5 ± 3.0 mg

LABA

none

10/10

  1. ICS inhaled corticosteroid, a fluticasone propionate equivalent dose, LABA: long-acting β2-agonist