Fig. 5
From: Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity
Effect of formoterol on immunopurified PTP-RR activity in U937 cells. a Cells were treated with formoterol (FM; 10−10-10−7 M), salmeterol (SM; 10−7 M) or salbutamol (SB; 10−7 M) for 20 min. b Cells stimulated with IL-2/IL-4 for 48 h were treated with FM (10−9 M) for 20 min. c Cells were preincubated with or without ICI-118551 (ICI; 10−5 M), a selective β2-adrenoceptor antagonist for 30 min, followed by treatment with FM (10−9 M) or cAMP inducer, forskolin (10−5 M). Data are expressed as fold change against non-treatment control (NT). Values represent means of four (a and b) or three (c) experiments ± SEM: # P < .05, ## P < .01 (vs. NT), and ** P < .01 (as shown between two groups)