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Fig. 4 | Respiratory Research

Fig. 4

From: Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity

Fig. 4

PTP-RR protein expression and its association with PP2A function and phosphorylation levels of GR and JNK1 in PBMCs. a PTP-RR expression in PBMCs from healthy volunteers (HV) and severe asthmatics (SA). Individual values and means of eight (HV) and ten (SA) subjects are shown. ## P < .01 (vs. HV). b Correlation between PTP-RR protein expression and PP2AC-Tyr307 phosphorylation (i), IP-PP2A activity (ii), PP2AC protein expression (iii), phosphorylation of GR-Ser226 (iv) and JNK1 (v) in PBMCs. Individual values (HV and SA) are shown and the dotted lines indicate 95% confidence interval

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