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Fig. 2 | Respiratory Research

Fig. 2

From: Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivity

Fig. 2

PTP-RR function under corticosteroid insensitive condition. a GR and JNK1 expression in PTP-RR-immunoprecipitates. b, c, d, e, f, U937 cells were exposed to IL-2/IL-4 for 48 h. PTP-RR protein expression (b) and activity (c) in whole cell extracts. GR (d) and JNK1 (e) protein expressions in PTP-RR-immunoprecipitates. Effect of MG-132 on PTP-RR expression (f). Data in (d) and (e) are expressed as fold change against non-treatment control (NT). Values represent means of four experiments ± SEM. # P < .05, ## P < .01 (vs. NT) and ** P < .01 (as shown between two groups)

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