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Table 2 Pearson’s correlation coefficients: weekly mean rescue medication doses and weekly mean night-time awakening scores

From: Effect of tiotropium on night-time awakening and daily rescue medication use in patients with COPD

Rescue medication correlation with night-time awakening

Tiotropium

Placebo

n

r

n

r

24 h

 Baseline

544

0.30***

357

0.34***

 Overall (Weeks 1–13)

543

0.41***

352

0.39***

6 pm to 6 am

 Baseline

544

0.39***

357

0.40***

 Overall (Weeks 1–13)

543

0.48***

352

0.51***

6 pm to midnight (12 am)

 Baseline

544

0.24***

357

0.26***

 Overall (Weeks 1–13)

543

0.34***

352

0.31***

Midnight (12 am) to 6 am

 Baseline

544

0.47***

357

0.43***

 Overall (Weeks 1–13)

543

0.55***

352

0.61***

6 am to 6 pm

 Baseline

544

0.20***

357

0.25***

 Overall (Weeks 1–13)

543

0.32***

352

0.26***

  1. ***p < 0.001