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Table 2 Pearson’s correlation coefficients: weekly mean rescue medication doses and weekly mean night-time awakening scores

From: Effect of tiotropium on night-time awakening and daily rescue medication use in patients with COPD

Rescue medication correlation with night-time awakening Tiotropium Placebo
n r n r
24 h
 Baseline 544 0.30*** 357 0.34***
 Overall (Weeks 1–13) 543 0.41*** 352 0.39***
6 pm to 6 am
 Baseline 544 0.39*** 357 0.40***
 Overall (Weeks 1–13) 543 0.48*** 352 0.51***
6 pm to midnight (12 am)
 Baseline 544 0.24*** 357 0.26***
 Overall (Weeks 1–13) 543 0.34*** 352 0.31***
Midnight (12 am) to 6 am
 Baseline 544 0.47*** 357 0.43***
 Overall (Weeks 1–13) 543 0.55*** 352 0.61***
6 am to 6 pm
 Baseline 544 0.20*** 357 0.25***
 Overall (Weeks 1–13) 543 0.32*** 352 0.26***
  1. ***p < 0.001