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Fig. 4 | Respiratory Research

Fig. 4

From: Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts

Fig. 4

TGF-β1 induces EMMPRIN Expression and MMP-2 activation in normal human lung fibroblasts; inhibition of MMP-2 activation by EMMPRIN functional blocking antibody: (a) A representative Western blot showing the expression of EMMPRIN in the cell lysates from NHLF stimulated with TGF-β1 compared to control untreated cells. β-Tubulin was used as the loading control. b A representative zymography demonstrating MMP-2 activation in the conditioned media from NHLF stimulated with TGF-β1 compared to the control untreated cells and inhibition of MMP-2 activation by EMMPRIN functional blocking antibody (n = 3 independent experiments, each run in duplicate)

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