Fig. 2From: Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblastsEMMPRIN overexpression induces phenotypic changes in normal human lung fibroblasts. Growth arrested NHLF transiently transfected with either EMMPRIN/GFP or GFP were treated with TGF- β1 5 and 10 ng/ml for 48 h. a Cell proliferation was assessed by thymidine incorporation. b Cell migration using Modified Boyden chamber. Each bar represents means ± SEM of 3 independent experiments each run in duplicates. ** p < 0.001 comparing GFP to EMMPRIN/GFP transfected cells, # p < 0.01 Comparing TGF- β1 treated cells to control. c A representative Western blot for α – smooth actin (α-SMA) of cell lysates from EMMPRIN/GFP and GFP control cells in the presence and absence of TGF-β1. β-Tubulin was used as the loading control. Image is representative of 3 independent experiments each run in duplicateBack to article page