Fig. 1

EMMPRIN overexpression in normal human lung fibroblasts (NHLF): NHLF were transiently transfected with either EMMPRIN/GFP or GFP alone and assessed for EMMPRIN expression using (a) Fluorescent microscopy demonstrating the distribution of GFP throughout the cell (left panel) in GFP control cells, while EMMPRIN-GFP cells primarily display cell-surface GFP expression (right panel). White Bar = 50 um. b Western blot analysis and (c) Gelatin zymography for MMP-2 release and activation (n = 10)