Variable | Low risk (n = 16) | High risk (n = 56) | p-value |
---|---|---|---|
Demographics | |||
 Age (yr) | 48.20 ± 17.34 | 51.80 ± 13.54 | 0.185 |
 Female, n (%) | 7 (44 %) | 4 (7 %) | <0.001 |
 BMI (kg/m2 ) | 23.82 ± 3.36 | 28.78 ± 7.41 | <0.001 |
 Neck circumference (cm) | 38.32 ± 2.77 | 42.20 ± 3.67 | <0.001 |
Medical history | |||
 Smoking status, n (%) | 3 (19 %) | 38 (67 %) | <0.001 |
 Alcohol, n (%) | 2 (12 %) | 23 (41 %) | <0.001 |
 Hypertension, n (%) | 3 (18 %) | 29 (53 %) | <0.001 |
 Diabetes mellitus, n (%) | 2 (13 %) | 12 (22 %) | 0.025 (<0.05) |
 Coronary artery disease, n (%) | 4 (25 %) | 8 (14 %) | 0.135 |
 Hyperlipidemia, n (%) | 7 (44 %) | 25 (45 %) | 0.897 |
Causes of deteriorated cardiac conduction | |||
 SA block or sinus arrest, n (%) | 8 (50 %) | 32 (57 %) | 0.618 |
 Complete AV block, n (%) | 7 (44 %) | 21 (38 %) | 0.657 |
 Combined forms of heart block, n (%) | 1 (6 %) | 3 (5 %) | 0.893 |
Cardiovascular medication | |||
 Platelet aggregation inhibitors, n (%) | 1 (6 %) | 7 (13 %) | 0.490 |
 Diuretic therapy, n (%) | 3 (19 %) | 18 (32 %) | 0.305 |
 ACE inhibitors/ARBs, n (%) | 2 (12 %) | 19 (34 %) | 0.125 |
 Statin therapy, n (%) | 2 (12 %) | 15 (27 %) | 0.241 |
Symptoms | |||
 Syncope, n (%) | 1 (6 %) | 7 (13 %) | 0.490 |
 Palpitations, n (%) | 2 (12 %) | 12 (21 %) | 0.433 |
 Chest pain, n (%) | 1 (6 %) | 4 (7 %) | 0.903 |
 Snoring, n (%) | 10 (63 %) | 48 (86 %) | 0.039 (<0.05) |
 Daytime sleepiness, n (%) | 8 (50 %) | 28 (57 %) | 0.618 |
ESS score | 7.07 ± 5.39 | 11.34 ± 6.19 | <0.001 |
Baseline Holter ECG | |||
 RR interval (>2 s, events/h) | 17.14 ± 26.30 | 196.06 ± 470.05 | 0.137 |
 Longest RR (>2 s, second) | 2.71 ± 0.86 | 3.56 ± 2.02 | 0.163 |
Baseline polysomnography | |||
 Obstructive and mixed apneas, n (%) | 0 (0 %) | 1 (2 %) | 0.597 |
 Obstructive apneas, n (%) | 11 (69 %) | 49 (88 %) | 0.022 (<0.05) |
 Central apneas, n (%) | 1 (6 %) | 1 (2 %) | 0.345 |
 AHI (events/h) | 12.94 ± 7.08 | 41.3 ± 17.85 | <0.001 |
 Mean SaO2 (%) | 96.14 ± 0.89 | 91.76 ± 3.90 | 0.008 (<0.01) |
 Oxygen saturation nadir (%) | 89 ± 5 | 86 ± 16 | 0.133 |