Dex | Dex/256066 | Dex/Rof | Dex/Forsk | ||
---|---|---|---|---|---|
Mean EC50 IL-2 | |||||
CD8 | COPD | 7.8 | 4.8 | 6.7 | 1.6 |
Smoker | 16.6 | 5.4 | 6.1 | 14.1 | |
HNS | 11.2 | 5.4 | 7.7 | 2.7 | |
PBMC | COPD | 8.91 | 11.4 | 4.2 | 2.2 |
Smoker | 22.9 | 8.3 | 8.7 | 18.2 | |
HNS | 12.0 | 4.9 | 3.8 | 2.0 | |
Mean EC50 IFNγ | |||||
CD8 | COPD | 10.0 | 4.0 | 5.0 | 1.6 |
Smoker | 20.0 | 6.3 | 7.9 | 10.0 | |
HNS | 15.8 | 12.6 | 3.2 | 5.0 | |
PBMC | COPD | 31.6 | 4.0 | 6.3 | 10.0 |
Smoker | 20.0 | 10.0 | 7.9 | 15.8 | |
HNS | 10.0 | 4.0 | 2.5 | 2.5 | |
Mean IC50 IL-2 | |||||
CD8 | COPD | 7.9 | 5.5 | 7.1 | 1.8 |
Smoker | 16.6 | 6.2 | 8.5 | 22.9 | |
HNS | 7.9 | 5.9 | 8.3 | 3.2 | |
PBMC | COPD | 8.5 | 30.2 | 4.8 | 1.6 |
Smoker | 22.9 | 6.6 | 9.3 | 33.9 | |
HNS | 10.7 | 5.5 | 6.5 | 3.1 | |
Mean IC50 IFNγ | |||||
CD8 | COPD | 12.0 | 3.6 | 4.6 | 1.9 |
Smoker | 18.2 | 8.1 | 7.4 | 11.0 | |
HNS | 21.4 | 8.1 | 3.6 | 0.8 | |
PBMC | COPD | 33.1 | 5.0 | 8.5 | 9.8 |
Smoker | 23.4 | 8.7 | 8.9 | 24.0 | |
HNS | 15.1 | 6.0 | 3.6 | 1.0 | |
Emax IL2 | |||||
CD8 | COPD | 67.9 | 78.1 | 78.2 | 86.6 |
Smoker | 68.5 | 86.5 | 81.9 | 80.9 | |
HNS | 66.3 | 82.0 | 80.7 | 79.7 | |
PBMC | COPD | 64.2 | 87.4 | 83.0 | 81.6 |
Smoker | 61.1 | 84.8 | 79.2 | 84.1 | |
HNS | 61.9 | 84.3 | 75.9 | 77.5 | |
Emax IFNγ | |||||
CD8 | COPD | 59.8 | 74.9 | 75.1 | 78.8 |
Smoker | 59.2 | 77.6 | 72.9 | 76.6 | |
HNS | 56.3 | 70.5 | 65.4 | 75.4 | |
PBMC | COPD | 69.7 | 86.4 | 82.2 | 85.7 |
Smoker | 66.0 | 84.0 | 83.6 | 75.4 | |
HNS | 61.0 | 83.2 | 82.9 | 73.7 |