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Fig. 3 | Respiratory Research

Fig. 3

From: IL-25 and IL-33 induce Type 2 inflammation in basophils from subjects with allergic asthma

Fig. 3

IL-25 and IL-33 up-regulate expression of their own receptor on basophils. Purified peripheral blood basophils from 8 allergic donors were suspended in RPMI-C and cultured for 18 h with PBS or optimal concentrations of anti-IgE, IL-3, TSLP, IL-25, or IL-33 (all 10 ng/mL), then assessed for percent basophil expression of (a) IL-17RB, (b) ST2, and (c) TSLPR. Data are expressed as mean ± SEM. *Significantly different from PBS negative control; P < 0.05 (N = 8)

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