Skip to main content
Fig. 6 | Respiratory Research

Fig. 6

From: Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1

Fig. 6

Effect of BMAL1 knockdown on TGF-β1-induced EMT of A549 human lung carcinoma cells. a A549 cells were transiently transfected with siBMAL1 or siCtrl for 72 h. During the last 48 h of transfection, the cells were treated with TGF-β1 at 5 ng/ml. a Western blot analysis was carried out to investigate the expression of EMT markers and BMAL1. * p < 0.05 vs. corresponding control siRNA groups stimulated with TGF-β1 (siCtrl-TGF-β1). b Immunofluorescent staining of E-cad in response to BMAL1 knockdown in A549 cells, 20× magnification, red, E-cad; Blue, DAPI

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us