| Univariate |  | Multivariable-adjusted |  |
---|---|---|---|---|
 | OR (95 % CI) | P-value | OR (95 % CI) | P-value |
Age | Â | Â | Â | Â |
  < 50 | Ref |  | Ref |  |
 50- <65 | 2.01 (1.92, 2.09) | <0.0001 | 1.45 (1.38, 1.51) | <0.0001 |
 65- <80 | 3.42 (3.23, 3.61) | <0.0001 | 1.67 (1.57, 1.77) | <0.0001 |
  ≥ 80 | 4.95 (4.65, 5.27) | <0.0001 | 1.90 (1.77, 2.03) | <0.0001 |
Gender | Â | Â | Â | Â |
 Female (ref) | Ref |  | Ref |  |
 Male | 0.98 (0.96, 1.00) | 0.0309 | 0.91 (0.89, 0.93) | <0.0001 |
Median household income | Â | Â | Â | Â |
 1st quartile (< $38,999) | Ref |  | Ref |  |
 2nd quartile ($39,000 to $47,999) | 1.14 (1.06, 1.23) | 0.0009 | 1.08 (1.00, 1.18) | 0.0509 |
 3rd quartile ($48,000 to $62999) | 1.40 (1.29, 1.53) | <0.0001 | 1.17 (1.07, 1.29) | 0.0012 |
 4th quartile ($63,000 or more) | 2.08 (1.86, 2.33) | <0.0001 | 1.45 (1.29, 1.63) | <0.0001 |
Primary payer | Â | Â | Â | Â |
 Medicare (ref) | Ref |  | Ref |  |
 Medicaid | 0.52 (0.49, 0.54) | <0.0001 | 0.91 (0.86, 0.96) | 0.0005 |
 Private insurance | 0.63 (0.60, 0.66) | <0.0001 | 0.98 (0.93, 1.03) | 0.4990 |
 Self-pay/no charge | 0.30 (0.28, 0.31) | <0.0001 | 0.70 (0.66, 0.74) | <0.0001 |
 Other | 0.63 (0.55, 0.72) | <0.0001 | 1.04 (0.93, 1.15) | 0.5203 |
Patient location (residence) | Â | Â | Â | Â |
 Micropolitan/not metropolitan | Ref |  | Ref |  |
 Metropolitan (large or small) | 1.70 (1.54, 1.89) | <0.0001 | 1.42 (1.27, 1.58) | <0.0001 |
Hospital Region | Â | Â | Â | Â |
 Northeast | Ref |  | Ref |  |
 Midwest | 0.54 (0.45, 0.64) | <0.0001 | 0.60 (0.51, 0.71) | <0.0001 |
 South | 0.66 (0.56, 0.79) | <0.0001 | 0.80 (0.67, 0.95) | 0.0106 |
 West | 0.58 (0.48, 0.69) | <0.0001 | 0.63 (0.52, 0.76) | <0.0001 |
Teaching status of hospital | Â | Â | Â | Â |
 Metropolitan non-teaching or non-metropolitan | Ref |  | Ref |  |
 Metropolitan teaching | 1.34 (1.17, 1.53) | <0.0001 | 1.14 (0.99, 1.30) | 0.0687 |
Comorbidities | Â | Â | Â | Â |
 CHD (ref: no) | 3.77 (3.55, 4.01) | <0.0001 | 1.89 (1.80, 1.99) | <0.0001 |
 Hyperlipidemia (ref: no) | 4.30 (3.98, 4.64) | <0.0001 | 2.35 (2.19, 2.51) | <0.0001 |
 Renal failure (ref: no) | 6.90 (6.33, 7.53) | <0.0001 | 3.10 (2.83, 3.39) | <0.0001 |
 CHF (ref: no) | 3.96 (3.73, 4.21) | <0.0001 | 2.13 (2.02, 2.25) | <0.0001 |
 Gout (ref: no) | 4.61 (4.08, 5.22) | <0.0001 | 1.87 (1.64, 2.14) | <0.0001 |
 Diabetes (ref: no) | 2.24 (2.14, 2.33) | <0.0001 | 1.19 (1.15, 1.24) | <0.0001 |
 Hypertension (ref: no) | 3.50 (3.31, 3.69) | <0.0001 | 1.93 (1.84, 2.02) | <0.0001 |
 Osteoarthritis (ref: no) | 6.83 (6.07, 7.67) | <0.0001 | 5.02 (4.42, 5.70) | <0.0001 |