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Table 2 Change-point regression for association with peak oxygen uptake (ml O2/min/kg)

From: Association between pulmonary function and peak oxygen uptake in elderly: the Generation 100 study

 

Change point (95 % CI)

Left slope (95 % CI)

Right slope (95 % CI)

Men:

 FEV1 (n = 729)

2.86 litres* (2.54, 3.17)

4.58† (2.85, 6.31)

0.60 (-0.56, 1.75)

 DLCO (n = 712)

9.18 mmol/min/kPa* (8.32, 10.05)

1.57† (1.06, 2.07)

0.16 (-0.37, 0.68)

 DLCO/VA (n = 712)

1.36 mmol/min/kPa/l (0.99, 1.74)

8.54† (4.32, 12.75)

4.99† (0.89, 9.08)

Women:

 FEV1 (n = 714)

2.13 litres * (1.93, 2.34)

3.76† (1.60, 5.92)

−0.84 (-2.22, 0.55)

 DLCO (n = 697)

5.50 mmol/min/kPa (4.45, 6.56)

1.54 (-0.04, 3.12)

0.31 (-0.01, 0.62)

 DLCO/VA (n = 697)

1.43 mmol/min/kPa/l (1.18, 1.68)

5.14† (2.37, 7.91)

1.25 (-2.30, 4.80)

  1. Definition of abbreviations: FEV1 = forced expiratory volume in 1 s; DLCO – diffusing capacity of the lung for carbon monoxide; DLCO/VA – DLCO corrected for estimated alveolar volume. Non-linear “Hockey-stick” regressions for the associations between pulmonary function variables and peak oxygen uptake. * p < 0.01 for hockey-stick model vs. linear model (f-test), † p < 0.01 for slope being different from 0
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Respiratory Research

ISSN: 1465-993X

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