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Table 2 Change-point regression for association with peak oxygen uptake (ml O2/min/kg)

From: Association between pulmonary function and peak oxygen uptake in elderly: the Generation 100 study

  Change point (95 % CI) Left slope (95 % CI) Right slope (95 % CI)
Men:
 FEV1 (n = 729) 2.86 litres* (2.54, 3.17) 4.58† (2.85, 6.31) 0.60 (-0.56, 1.75)
 DLCO (n = 712) 9.18 mmol/min/kPa* (8.32, 10.05) 1.57† (1.06, 2.07) 0.16 (-0.37, 0.68)
 DLCO/VA (n = 712) 1.36 mmol/min/kPa/l (0.99, 1.74) 8.54† (4.32, 12.75) 4.99† (0.89, 9.08)
Women:
 FEV1 (n = 714) 2.13 litres * (1.93, 2.34) 3.76† (1.60, 5.92) −0.84 (-2.22, 0.55)
 DLCO (n = 697) 5.50 mmol/min/kPa (4.45, 6.56) 1.54 (-0.04, 3.12) 0.31 (-0.01, 0.62)
 DLCO/VA (n = 697) 1.43 mmol/min/kPa/l (1.18, 1.68) 5.14† (2.37, 7.91) 1.25 (-2.30, 4.80)
  1. Definition of abbreviations: FEV1 = forced expiratory volume in 1 s; DLCO – diffusing capacity of the lung for carbon monoxide; DLCO/VA – DLCO corrected for estimated alveolar volume. Non-linear “Hockey-stick” regressions for the associations between pulmonary function variables and peak oxygen uptake. * p < 0.01 for hockey-stick model vs. linear model (f-test), † p < 0.01 for slope being different from 0