Variables | HNPs in BALF | IL-8 in BALF | |||||
---|---|---|---|---|---|---|---|
N | r | 95 % CI | P-value | r | 95 % CI | P-value | |
HNPs in plasma | 33 | 0.049 | −0.299 – 0.386 | 0.79 | −0.06 | −0.395 – 0.289 | 0.75 |
HNPs in BALF | 33 | – | – | – | 0.774 | 0.587 – 0.883 | <0.01 |
IL-8 in serum | 33 | 0.324 | −0.022 – 0.600 | 0.07 | 0.160 | −0.194 – 0.477 | 0.38 |
IL-8 in BALF | 33 | 0.774 | 0.587 – 0.883 | <0.01 | – | – | – |
Laboratory data | |||||||
PaO2 (torr) | 28 | −0.416 | −0.683 – −0.051 | 0.03 | −0.429 | −0.691 – −0.067 | 0.02 |
KL-6 (U/mL) | 30 | 0.511 | 0.185 – 0.736 | <0.01 | 0.467 | 0.128 – 0.708 | <0.01 |
SP-D (ng/mL) | 33 | 0.363 | 0.023 – 0.628 | 0.04 | 0.360 | 0.019 – 0.626 | 0.04 |
SP-A (ng/mL) | 25 | 0.256 | −0.155 – 0.591 | 0.23 | 0.364 | −0.36 – 0.664 | 0.08 |
Pulmonary function test | |||||||
%VC (%) | 33 | −0.575 | −0.767 – −0.289 | <0.01 | −0.636 | −0.804 – −0.374 | <0.01 |
FEV1/FEV (%) | 33 | 0.106 | −0.246 – 0.434 | 0.56 | −0.091 | −0.421 – 0.260 | 0.61 |
%DLco (%) | 32 | −0.529 | −0.741 – −0.221 | <0.01 | −0.492 | −0.718 – −0.173 | <0.01 |
BALF cell findings | |||||||
TCC (× 105/mL) | 33 | −0.036 | −0.375 – 0.311 | 0.84 | −0.065 | −0.399 – 0.285 | 0.72 |
Macrophages (%) | 33 | 0.016 | −0.329 – 0.357 | 0.93 | −0.010 | −0.352 – 0.335 | 0.96 |
Lymphocytes (%) | 33 | −0.153 | −0.472 – 0.201 | 0.40 | −0.167 | −0.483 – 0.187 | 0.35 |
Neutrophils (%) | 33 | 0.595 | 0.316 – 0.779 | <0.01 | 0.540 | 0.242 – 0.745 | <0.01 |
Eosinophils (%) | 33 | 0.466 | 0.146 – 0.698 | <0.01 | 0.419 | 0.088 – 0.666 | 0.02 |
CD4/8 (%) | 33 | −0.090 | −0.420 – 0.261 | 0.62 | −0.009 | −0.351 – 0.335 | 0.96 |
HRCT findings | |||||||
Ground glass opacity (%) | 33 | 0.711 | 0.486 – 0.848 | <0.01 | 0.583 | 0.230 – 0.772 | <0.01 |
Reticular opacities (%) | 33 | 0.652 | 0.398 – 0.813 | <0.01 | 0.605 | 0.330 – 0.785 | <0.01 |
TRPG | 30 | 0.517 | 0.193 – 0.740 | <0.01 | 0.473 | 0.136 – 0.712 | <0.01 |
Decline in absolute VC (%) | |||||||
One year | 15 | −0.275 | −0.690 – 0.276 | 0.32 | −0.059 | −0.555 – 0.467 | 0.84 |
Two years | 12 | −0.070 | −0.619 – 0.525 | 0.83 | 0.010 | −0.567 – 0.581 | 0.97 |