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Table 2 Demographic characteristics

From: Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Cohort Healthy Controls Mild Moderate Severe Total
No. Subjects 30 52 55 51 188
USA 3 (10 %) 11 (21 %) 15 (27 %) 12 (24 %) 41 (22 %)
Canada 12 (39 %) 10 (19 %) 12 (22 %) 17 (33 %) 51 (27 %)
EU, ex-Romania 9 (29 %) 21 (40 %) 17 (31 %) 11 (22 %) 58 (31 %)
Romania 7 (23 %) 10 (19 %) 11 (20 %) 11 (22 %) 39 (21 %)
Cohort Healthy Controls Mild Moderate Severe P-value *
Age (yrs)      <0.0001/<0.0001
 Mean (SD) 31.6 (9.2) 33.7 (13.1) 45.0 (11.6) 46.2 (12.1)  
 Range (18; 54) (18; 64) (18; 65) (18; 65)  
Male Sex 19 (63.3 %) 20 (38.5 %) 27 (49.1 %) 23 (45.1 %) 0.14/0.54
Race      0.43/0.27
 White 27 (90.0 %) 46 (88.5 %) 47 (85.5 %) 41 (80.4 %)  
 Black or African American 1 (3.3 %) 1 (1.9 %) 5 (9.1 %) 7 (13.7 %)  
 Asian 2 (6.7 %) 4 (7.7 %) 3 (5.5 %) 2 (3.9 %)  
 Other 0 1 (1.9 %) 0 1 (2.0 %)  
BMI (kg/m2)      0.034 /0.094
 Mean (SD) 24.6 (3.4) 25.2 (3.4) 26.4 (3.5) 26.7 (4.1)  
 Range (17.5; 29.5) (19.4; 31.9) (18.8; 32.0) (19.1; 36.8)  
Duration asthma (yrs)      NA/0.094
 Mean (SD) NA 17.4 (11.9) 22.0 (13.6) 22.7 (14. 0)  
 Range NA (0.7; 64.0) (1.5; 56.3) (0.3; 50.5)  
  1. *p-value (ANOVA F-test, or Fisher’s exact test when N, % reported) for differences across severity cohorts, including/excluding healthy control cohort