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Table 2 Demographic characteristics

From: Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Cohort

Healthy Controls

Mild

Moderate

Severe

Total

No. Subjects

30

52

55

51

188

USA

3 (10 %)

11 (21 %)

15 (27 %)

12 (24 %)

41 (22 %)

Canada

12 (39 %)

10 (19 %)

12 (22 %)

17 (33 %)

51 (27 %)

EU, ex-Romania

9 (29 %)

21 (40 %)

17 (31 %)

11 (22 %)

58 (31 %)

Romania

7 (23 %)

10 (19 %)

11 (20 %)

11 (22 %)

39 (21 %)

Cohort

Healthy Controls

Mild

Moderate

Severe

P-value *

Age (yrs)

    

<0.0001/<0.0001

 Mean (SD)

31.6 (9.2)

33.7 (13.1)

45.0 (11.6)

46.2 (12.1)

 

 Range

(18; 54)

(18; 64)

(18; 65)

(18; 65)

 

Male Sex

19 (63.3 %)

20 (38.5 %)

27 (49.1 %)

23 (45.1 %)

0.14/0.54

Race

    

0.43/0.27

 White

27 (90.0 %)

46 (88.5 %)

47 (85.5 %)

41 (80.4 %)

 

 Black or African American

1 (3.3 %)

1 (1.9 %)

5 (9.1 %)

7 (13.7 %)

 

 Asian

2 (6.7 %)

4 (7.7 %)

3 (5.5 %)

2 (3.9 %)

 

 Other

0

1 (1.9 %)

0

1 (2.0 %)

 

BMI (kg/m2)

    

0.034 /0.094

 Mean (SD)

24.6 (3.4)

25.2 (3.4)

26.4 (3.5)

26.7 (4.1)

 

 Range

(17.5; 29.5)

(19.4; 31.9)

(18.8; 32.0)

(19.1; 36.8)

 

Duration asthma (yrs)

    

NA/0.094

 Mean (SD)

NA

17.4 (11.9)

22.0 (13.6)

22.7 (14. 0)

 

 Range

NA

(0.7; 64.0)

(1.5; 56.3)

(0.3; 50.5)

 
  1. *p-value (ANOVA F-test, or Fisher’s exact test when N, % reported) for differences across severity cohorts, including/excluding healthy control cohort