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Table 1 Categorization of asthma severity based upon background therapy and lung function

From: Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

  Pre-BD FEV1 ≥ 80 % predicted normal Pre-BD FEV1 ≥ 60- < 80 % predicted normal Pre-BD FEV1 ≥ 50- < 60 % predicted normal Pre-BD FEV1 < 50 % predicted normal
Controller medication
None Eligible for mild asthma cohort Ineligible Ineligible Ineligible
Low to medium ICS alone or in combination with other controllers except chronic oral corticosteroids and omalizumab Ineligible Eligible for moderate asthma cohort Ineligible Ineligible
High dose ICS alone or in combination with other controllers including chronic oral corticosteroids and omalizumab Ineligible Eligible for severe asthma cohort Eligible for severe asthma cohort Ineligible