Table 3 Hemodynamic response to adaptive servoventilation in patients with pre-capillary pulmonary hypertension (n = 21)
Baseline | Intervention | Recovery | p* | |
|---|---|---|---|---|
Systolic blood pressure (mmHg) | 117 ± 18 | 111 ± 13 | 119 ± 16 | 0.087 |
Diastolic blood pressure (mmHg) | 65 ± 14 | 65 ± 9 | 68 ± 11 | 0.971 |
Heart rate (min−1) | 69 ± 10 | 63 ± 11 | 66 ± 10 | <0.001 |
Right atrial pressure (mmHg) | 11 ± 4 | 13 ± 4 | 11 ± 5 | 0.002 |
Mean pulmonary artery pressure (mmHg) | 46 ± 13 | 42 ± 12 | 44 ± 11 | 0.003 |
Pulmonary arterial wedge pressure (mmHg) | 10 ± 3 | 15 ± 4 | 11 ± 3 | <0.001 |
Cardiac output (l/min) | 4.1 ± 1.1 | 3.6 ± 1.2 | 4.2 ± 1.3 | 0.001 |
Cardiac index (L/min/m2) | 2.2 ± 0.4 | 1.9 ± 0.4 | 2.2 ± 0.4 | <0.001 |
Stroke volume (ml/min) | 62 ± 20 | 59 ± 20 | 63 ± 20 | 0.15 |
Pulmonary vascular resistance (dyn · s · cm−5) | 754 ± 367 | 711 ± 372 | 750 ± 395 | 0.20 |
Peripheral oxygen saturation (%) | 93 ± 2 | 97 ± 4 | 93 ± 3 | <0.001 |
Mixed venous oxygen saturation (%) | 65 ± 6 | 68 ± 6 | 62 ± 10 | 0.022 |
Mixed venous pCO2 (mmHg) | 41 ± 5 | 37 ± 6 | 39 ± 8 | 0.001 |