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Table 1 Baseline demographics and clinical characteristics

From: Small airway epithelial-C/EBPβ is increased in patients with advanced COPD

Parameter

Never smokers

Smokers w/o COPD

GOLD I-II COPDb

GOLD III-IV COPDc

p ANOVA

Subjects (n)a

8

6

18

12

 

Gender (female/male)

6/2

3/3

5/13

6/6

 

Age (years)

63 ± 4.8

56 ± 3.2

68 ± 1.8

61 ± 1.2

<0.05

Height (m)

1,64 ± 0.033

1.72 ± 0.05

1,74 ± 0.02

1,7 ± 0.031

ns

Weight (kg)

64,6 ± 4.6

69.2 ± 4.4

73,1 ± 3.5

67,7 ± 4.1

ns

Body mass index

23,9 ± 1.3

23.3 ± 1.1

24,4 ± 1.1

23,3 ± 0.94

ns

Pack years

N/A

43 ± 9.7

45 ± 3.5

41 ± 3.2

ns

Smoker/ex-smoker

N/A

3/3

7/11

0/12

 

FEV1/FVC

85,9 ± 5.7

77.8 ± 2.4

61,4 ± 1.9

33,4 ± 2.1

<0.001

FEV1 (% of predicted)

109,8 ± 6.2

93.8 ± 4.2

74,1 ± 2.7

26,2 ± 2.7

<0.001

Corticosteroids (yes/no/unknown)

0/8/0

0/6/0

2/16/0

9/2/1

 

Bronchodialator (yes/no/unknown)

0/8/0

0/6/0

6/12/0

9/2/1

 
  1. aAll surgeries were performed at Skåne University Hospital, in Lund, Sweden
  2. bTissue samples were obtained during lung resection surgery for bronchial tumour
  3. cTissue samples were obtained from GOLD II COPD patients during lung resection surgery for bronchial tumour, and from GOLD IV COPD patients during lung transplantation