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Table 1 Baseline demographics and clinical characteristics

From: Small airway epithelial-C/EBPβ is increased in patients with advanced COPD

Parameter Never smokers Smokers w/o COPD GOLD I-II COPDb GOLD III-IV COPDc p ANOVA
Subjects (n)a 8 6 18 12  
Gender (female/male) 6/2 3/3 5/13 6/6  
Age (years) 63 ± 4.8 56 ± 3.2 68 ± 1.8 61 ± 1.2 <0.05
Height (m) 1,64 ± 0.033 1.72 ± 0.05 1,74 ± 0.02 1,7 ± 0.031 ns
Weight (kg) 64,6 ± 4.6 69.2 ± 4.4 73,1 ± 3.5 67,7 ± 4.1 ns
Body mass index 23,9 ± 1.3 23.3 ± 1.1 24,4 ± 1.1 23,3 ± 0.94 ns
Pack years N/A 43 ± 9.7 45 ± 3.5 41 ± 3.2 ns
Smoker/ex-smoker N/A 3/3 7/11 0/12  
FEV1/FVC 85,9 ± 5.7 77.8 ± 2.4 61,4 ± 1.9 33,4 ± 2.1 <0.001
FEV1 (% of predicted) 109,8 ± 6.2 93.8 ± 4.2 74,1 ± 2.7 26,2 ± 2.7 <0.001
Corticosteroids (yes/no/unknown) 0/8/0 0/6/0 2/16/0 9/2/1  
Bronchodialator (yes/no/unknown) 0/8/0 0/6/0 6/12/0 9/2/1  
  1. aAll surgeries were performed at Skåne University Hospital, in Lund, Sweden
  2. bTissue samples were obtained during lung resection surgery for bronchial tumour
  3. cTissue samples were obtained from GOLD II COPD patients during lung resection surgery for bronchial tumour, and from GOLD IV COPD patients during lung transplantation