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Fig. 3 | Respiratory Research

Fig. 3

From: TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma

Fig. 3

Airway responsiveness after TNFα blockade on TLR3 and TLR4 stimulation. a Newtonian resistance (R N ), (b) tissue damping (G) and (c) tissue elastance (H) measured in PBS-treated mice (control) with one daily intranasal administration of 20 μg poly(I:C) + 2 μg LPS (P + L) for four days with and without infliximab treatment. d Newtonian resistance (R N ), (e) tissue damping (G) and (f) tissue elastance (H) measured in OVA-sensitized and challenged mice treated with one daily intranasal administration of 20 μg poly(I:C) + 2 μg LPS for four days with and without infliximab treatment. Results are shown as mean ± S.E.M. Lines between symbols represent P < 0.05; n = 8–13

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Respiratory Research

ISSN: 1465-993X

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