Fig. 3
From: Cigarette smoke differentially modulates dendritic cell maturation and function in time
Long-term continuous exposure to CSE suppresses the development of functional DCs from BM precursors. BM precursors were cultured in the presence or absence of CSE (1.5 %) or LPS (100 ng/ml, as positive control) continuously with every feeding day. Representative dot plots, (panels a and c) and bars (panels b and d) show percentages of DCs positive for CD11c-MHCII (a, b) CD11c-CD86 and -CD40 (c, d). Data in A and C show one representative experiment of seven. Data represent mean ± S.E.M. *P < 0.05, **P < 0.01 significantly different compared to control and ^^ P < 0.01 significantly different compared to LPS 24 h