Fig. 5

PαS MSC treatment modulates CD86 costimulatory molecule expression on CD103⁺ respiratory DC after K. pneumoniae infection. Representative flow cytometry analysis of CD86, CD274 (PD-L1) and MHC-class II expression on CD103⁺ respiratory DC in K. pneumoniae-infected animals treated with PαS MSC versus mock-treated infected animals at 48 h p.i. (a). Quantitative analysis of median fluorescence intensity (MFI) on respiratory DC subsets in K. pneumoniae-infected (Kpn) animals treated with PαS MSC versus controls at 48 h p.i. (b). Mean ± SEM; n ≥ 6 (48 h p.i.); n ≥ 4 (d5 p.i.).***p < 0.001 versus mock-treated infected controls. Data from n = 2 (A-B) experiments