Fig. 2

PαS MSC inhibit alveolar TNF-α, IL-12p70 and acute lung injury after K. pneumoniae infection. K. pneumoniae infected animals were treated with PαS MSC (4 h p.i.). Analysis of body weight (a) and flow cytometry-based quantitation of alveolar leukocytes, granulocytes and macrophages (b-e). Alveolar protein (f) and alveolar cytokines TNF-α (g), IL-12p70 (h) and IL-10 (i) were quantified by cytometric bead array. Mean ± SEM; n ≥ 3 (a, c-e); n ≥ 4 (f); n ≥ 6 (g-i). *p < 0.05; **p < 0.01; ***p < 0.001 versus mock-treated infected controls. Data from n ≥ 2 (a-i) experiments. Kpn, infected with K. pneumoniae