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Table 6 Change in panenterhino/Ge/08 assay viral load in nasal secretions - patients with quantifiable baseline viral load, ANCOVA-adjusted means

From: Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial

   

I-C vs. placebo

 

N

Adjusteda mean (SE)

Adjusteda mean (SE) differenceb

95 % CI

p-value*

Baseline [log (copies/mL)]c

     

 I-C

22

5.840 (0.200)

   

 Placebo

24

6.139 (0.201)

   

Change from baseline, [log (copies/mL)]

     

 I-C

22

−1.007 (0.191)

−0.453 (0.266)

−0.990, 0.084

0.0958

 Placebo

24

−0.554 (0.183)

   

Reduction from baseline (%)c,d

     

 I-C

22

90.2

   

 Placebo

24

72.0

   
  1. CI confidence interval, SE standard error
  2. *For ANCOVA-adjusted comparison of placebo with I-C
  3. aThe means were adjusted for baseline viral load
  4. bA negative treatment difference favored I-C
  5. cBaseline values are unadjusted means
  6. dCalculated according to Eccles et al. [5]