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Table 2 Total symptom scores over Days 2 to 4 (TSS2-4), ANCOVA-adjusted means, FAS

From: Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial

    I-C vs. placebo
  N Adjusteda mean (SE) Adjusteda mean (SE) differenceb 95 % CI p-value*
TSS0 c      
 I-C 98 6.75 (0.17)    
 Placebo 97 6.79 (0.18)    
TSS2-4      
 I-C 98 5.78 (0.25) −0.61 (0.36) (-1.32, 0.10) 0.0895
 Placebo 97 6.39 (0.25)    
  1. CI confidence interval, SE standard error
  2. *For ANCOVA-adjusted comparison of placebo with I-C
  3. aThe means were adjusted for TSS0
  4. bA negative treatment difference favored I-C
  5. cTSS0 values are unadjusted means