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Table 3 Correlations between function measurements and serum matrix metalloproteinases in IPFa

From: Matrix metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis

 

MMP-1

MMP-2

MMP-3

MMP-7

MMP-8

MMP-9

MMP-10

MMP-12

%FVC

-0.308*

-0.344

%DLCO

-0.251

-0.316*

−0.434

6MWD

−0.355

−0.228

−0.384

−0.309*

Minimum SpO2 during the 6MWT

−0.235

−0.261

−0.416

PaO2 in room air

−0.318*

  1. The data are shown as Spearman’s ρ when the p-value < 0.10
  2. IPF idiopathic pulmonary fibrosis, MMP matrix metalloproteinase, %FVC percentage of predicted forced vital capacity, %DL CO percentage of predicted diffusing capacity of the lung for carbon monoxide, 6MWD 6-minute walk distance, SpO 2 oxygen saturation, 6MWT 6-minute walk test, PaO 2 partial pressure of oxygen
  3. aMMP-13 was excluded from the analysis
  4. * p < 0.05, p < 0.01