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Table 1 Patient characteristics

From: Matrix metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis

 

IPF

COPD

Control

p-value

p-value

p-value

(n = 57)

(n = 20)

(n = 15)

IPF vs. Control

IPF vs. COPD

COPD vs. Control

Age, years

69.4 ± 8.5

70.8 ± 7.1

65.9 ± 7.9

NS

NS

NS

Gender, male

51 (89.5)

19 (95.0)

15 (100)

NS

NS

NS

Current or former smoker

53 (93.0)

20 (100)

7 (46.7)

<0.001

NS

<0.001

Patients who underwent BAL

25 (43.9)

   

Patients who underwent SLB

10 (17.5)

   

FVC, % predicted

84.2 ± 21.3

93.5 ± 20.1

 

NS

 

DLCO, % predicted

43.7 ± 14.2

56.6 ± 17.5

 

0.004

 

6MWD, m

454 ± 108

   

Minimum SpO2 during 6MWT, %

85.7 ± 8.4

   

PaO2 at room air, Torr

82.6 ± 13.1

   
  1. The data are presented either as the number (%) or mean ± standard deviation
  2. IPF idiopathic pulmonary fibrosis, COPD chronic obstructive pulmonary disease, NS not significant, BAL bronchoalveolar lavage, BALF bronchoalveolar lavage fluid, SLB surgical lung biopsy, FVC forced vital capacity, DL CO diffusing capacity of the lung for carbon monoxide, 6MWD 6-minute walk distance, SpO 2 oxygen saturation, 6MWT 6-minute walk test, PaO 2 partial pressure of oxygen