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Fig. 9 | Respiratory Research

Fig. 9

From: The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4

Fig. 9

Effect of O3 on pulmonary antioxidant, neuropeptide, and neutrophilic chemokines expression in adult (6-week old) TLR4−/− mice compared to wild-type (WT) mice. (a) metallothionein-1 (MT1), (b) heme oxygenase-1 (HMOX-1), (c) calcitonin gene-related peptide (CGRP), (d) chemokine (C-X-C) ligand 1 (CXCL1), (e) chemokine (C-X-C) ligand 2 (CXCL2), (f) chemokine (C-X-C) ligand 5 (CXCL5). Expression was analyzed by real-time qPCR and was normalized to GAPDH. Data are presented as mean ± SEM (n = 5–6 mice/group). *: p < 0.05, compared with age-matched FA-exposed controls; #: Statistical difference between the groups (p < 0.05)

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