Fig. 4
From: The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4
Age-related effects of O3 on airway mucus expression and release. (a) Muc5ac was detected in tissue of central intrapulmonary airways by immunohistochemistry (brown staining) and was localized to the airway epithelium. Scale bar represents 200 μm. (b) Epithelial Muc5ac expression was quantified by morphometry. The data are expressed as area of Muc5ac-positive epithelium normalized to the perimeter of the epithelial basement membrane (mean ± SEM, n = 3–4/group). (c) Levels of Muc5ac measured in the BAL fluids (mean ± SEM, n = 3-7/group). *: p < 0.05, compared with age-matched FA-exposed controls