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Fig. 3 | Respiratory Research

Fig. 3

From: Inhaled carbon monoxide protects time-dependently from loss of hypoxic pulmonary vasoconstriction in endotoxemic mice

Fig. 3

Baseline pulmonary artery pressure during normoxic ventilation; a. Average values of baseline pulmonary artery pressure (= PAP) during ventilation with 21 % O2 in lungs obtained from saline-treated controls (open bars) and from lipopolysaccharide-treated mice (LPS, black bars) after exposure to air or to 50 ppm CO for 18 h. Baseline PAP during nomoxic ventilation was not altered by LPS treatment or CO exposure. b. Average values of baseline PAP in lungs obtained from LPS-treated mice after exposure to 50 ppm CO for the first 6 h, the last 12 h, the first 3 h and the second 3 h after LPS challenge. Baseline PAP in LPS-treated animals was not affected by CO, independently of time and duration of CO exposure compared to CO exposure for 18 h. For better comparability values for the group (LPS/CO 18 h) are also depicted in figure B. Data are presented in mmHg as mean ± SD; n = 8 per group

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