Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study

Respiratory Research

Table 5 Effect of Childhood Pneumonia on Chest CT Parameters

	Impact of Childhood Pneumonia^b
	β^c	SE	p Value^d
Wall Area %, Segmental	0.46	(0.12)	<0.001
Wall Area %, Subsegmental^a	0.47	(0.16)	0.003
SRWA-Pi10	0.02	(0.005)	<0.001
Emphysema % (-950 HU)	0.18	(0.32)	0.57
Gas Trapping %, expiratory scan (-856HU)	1.97	(0.72)	0.006
Total Lung Capacity (L)	0.001	(0.04)	0.99

Abbreviations: CT computed tomography; HU Hounsfield units; SRWA-Pi10 square root wall area of a hypothetical airway with 10mm internal perimeter
^aData only available for a limited portion of the cohort
^bEach row represents a separate regression model
^cBeta coefficient (β) and standard error (SE) for linear regression
^dCovariates used = age at enrollment in years + gender + race + pack-years + body mass index + CT scanner model

ISSN: 1465-993X