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Fig. 6 | Respiratory Research

Fig. 6

From: MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment

Fig. 6

Important role of hematopoietic cells mediating ODE-induced inflammatory cytokine/chemokine release. MyD88 bone marrow chimeric mice (donor → recipient) were treated once with ODE or saline and at five hr post treatment, TNF-α, IL-6 and the murine neutrophil IL-8 chemokine homologs (CXCL1 and CXCL2) were determined in BALF. The data represent mean with standard error bars shown (N = 10–15 mice per ODE; N = 4–8 mice per saline treatment group). Statistical significance denoted by asterisks (p < 0.01, ***p < 0.001) as compared to respective saline treatment group. Line denotes statistical significance of chimera mice to WT mice treated with ODE

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