TY - JOUR AU - Broos, Caroline E. AU - van Nimwegen, Menno AU - Kleinjan, Alex AU - ten Berge, Bregje AU - Muskens, Femke AU - in ’t Veen, Johannes C.C.M. AU - Annema, Jouke T. AU - Lambrecht, Bart N. AU - Hoogsteden, Henk C. AU - Hendriks, Rudi W. AU - Kool, Mirjam AU - van den Blink, Bernt PY - 2015 DA - 2015/09/16 TI - Impaired survival of regulatory T cells in pulmonary sarcoidosis JO - Respiratory Research SP - 108 VL - 16 IS - 1 AB - Impaired regulatory T cell (Treg) function is thought to contribute to ongoing inflammatory responses in sarcoidosis, but underlying mechanisms remain unclear. Moreover, it is not known if increased apoptotic susceptibility of Tregs may contribute to an impaired immunosuppressive function in sarcoidosis. Therefore, the aim of this study is to analyze proportions, phenotype, survival, and apoptotic susceptibility of Tregs in sarcoidosis. SN - 1465-993X UR - https://doi.org/10.1186/s12931-015-0265-8 DO - 10.1186/s12931-015-0265-8 ID - Broos2015 ER -