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Fig. 2 | Respiratory Research

Fig. 2

From: Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosis

Fig. 2

Uridine supplementation decreases inflammation and fibrosis in the late phase after intratracheal bleomycin administration. Animals were treated with i. t. bleomycin on day 0. Uridine or vehicle was administered three times a week starting from day 14. Animals were assessed for inflammation and fibrosis at day 30. a BALF differential cell counts. b BALF cytokine levels. c HE stainings of lung sections. d BALF collagen content. e Collagen content on histological lung slides. Data are means ± SEM, n = 4–6 mice per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p <  0,0001. The experiment was repeated twice with similar results

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