Fig. 1From: Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosisUridine supplementation decreases inflammation in the early phase after intratracheal bleomycin administration. Animals were treated with i. t. bleomycin on day 0. Uridine or vehicle was administered after 6 h, at day 5 and at day 10. Animals were assessed for inflammation and fibrosis at day 7 and day 14. a BALF differential cell counts. b BALF cytokine levels. c HE stainings of lung sections. d BALF collagen content. e Collagen content on histological lung slides. Data are means ± SEM, n = 4–6 mice per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0,0001. The experiment was repeated twice with similar resultsBack to article page