Fig. 5
From: Complementary roles of KCa3.1 channels and β1-integrin during alveolar epithelial repair
ATII wound repair stimulation with 1-EBIO. ATII cell monolayers grown for 3 days in the absence or presence of fibronectin coating were treated with increasing 1-EBIO concentrations (50, 100 and 200 μM) before wounding and wound-repair rates (in μm2/h) were measured over a 24-h period (n = 7). Representative photographs (x4 magnification) at time 0 (T0) and 24 h (T24) after injury in the presence or absence of 100 μM 1-EBIO are presented in the upper panel.* p < 0.05. Two-way Anova statistical analysis revealed that both the coating (p = 0.01) and 1-EBIO (p = 0.007) elicited a significant effect on the wound repair rates. Moreover, the values of the fibronectin group (1-EBIO (0, 50, 100, 200 μM) + fibronectin) were statistically higher than the values of the uncoated group (1-EBIO (0, 50, 100, 200 μM), no coating)