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Fig. 2 | Respiratory Research

Fig. 2

From: Quantitation of circulating wild-type alpha-1-antitrypsin in heterozygous carriers of the S and Z deficiency alleles

Fig. 2

a. Comparison of quantitation of total A1AT in M/M homozygotes (n = 244). Total A1AT concentration by LC-MS/MS using the proteotypic peptide (y-axis) compared to the concentration measured by immuno-nephelometry (x-axis). b. Comparison of total A1AT by nephelometry and LC-MS/MS in M/S heterozygous patients (n = 63). c. Comparison of total A1AT by nephelometry and LC-MS/MS in M/Z heterozygous patients (n = 61). d. Total A1AT in the M/M cohort by LC-MS/MS using the proteotypic peptide (y-axis) compared to total A1AT by LC-MS/MS using the non-S peptide (x-axis). e. Total A1AT in the M/M cohort by LC-MS/MS using the proteotypic peptide (y-axis) compared to total A1AT by LC-MS/MS using the non-Z peptide (x-axis)

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