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Table 7 BP and BD responses to sulforaphane (SF) arranged according to changes in forced expiratory volume in 1-second (FEV1) to MCh (mean ± SD). A. Non-smokers (n = 30), B. Smokers (n = 15).

From: Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways

A. Non-smokers

 

BP (% change)

BD (% change)

 

Before SF

After SF

p for SF effect

Before SF

After SF

p for SF effect

Decreased FEV1 response to MCh

40.4 ± 40.4

−3.8 ± 46.8

0.002

33.7 ± 39.4

23.8 ± 36.8

0.20

Increased FEV1 response to MCh

−49.3 ± 29.7

23.5 ± 35.8

0.004

17.7 ± 27.0

36.3 ± 17.7

0.04

B. Smokers

 

BP (% change)

BD (% change)

 

Before SF

After SF

p for SF effect

Before SF

After SF

p for SF effect

Decreased FEV1 response to MCh

32.3 ± 34.2

5.1 ± 91.1

0.28

47.1 ± 21.8

22.1 ± 33.4

0.06

Increased FEV1 response to MCh

17.1 ± 60.7

48.1 ± 20.6

0.44

22.3 ± 23.1

27.4 ± 20.1

0.63