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Table 6 Change in oxidative stress gene expression related to changes in Forced Expiratory Volume in 1 second (FEV1) in response to single dose MCh challenge (mean ± SD). P-value for pre vs. post sulforaphane

From: Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways

  Gene Expression (% change from baseline)
GST1 NQO1 GCLM
Decreased FEV1 response to MCh −6.11 ± 27.0 −73.1 ± 255.4 −19.2 ± 40.6
p = 0.67 p = 0.23 p = 0.03
Increased FEV1 response to MCh 11.8 ± 56.0 141.9 ± 283.7 32.4 ± 75.0
p = 0.38 p = 0.047 p = 0.58