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Fig. 7 | Respiratory Research

Fig. 7

From: Building a better neonatal mouse model to understand infant respiratory syncytial virus disease

Fig. 7

Reinfection of rA2-19F worsened lung pathology. Pups were infected and reinfected as young adults with media, rA2-19F or A2. Six days post reinfection, lungs were isolated, fixed, and stained for histopathology. ac H&E staining for inflammation. Scale bar = 100um. Arrows indicate inflammatory cell aggregates. df PAS staining for airway mucus production. Scale bar =400 um. Arrows indicate mucus producing cells. Sham/Sham: mice initially infected with media as neonates and reinfected with media as young adults; A2/A2: mice initially infected with A2 as neonates and reinfected with A2 as young adults; rA2-19F/rA2-19F: mice initially infected with rA2-19F as neonates and reinfected with rA2-19F as young adults. The figure is a representative of 2 independent experiments; 3 mice per experiment time point

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