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Table 2 Microbiological analysis of BAL samples

From: Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection

 

Stable COPD n = 53

AE-COPD n = 44

Bacteriology positive

22 (41.5)

21 (47.7)

n (% of patients)

Gram staining

  

Gram positive cocci

14 (26.4)

13 (29.5)

Gram positive rods

9 (17.0)

4 (9.1)

Gram negative rods

6 (11.3)

7 (15.9)

Culture

  

Streptococcus pneumonia

4 (7.5)

-

Streptococcus pyogenes

-

2 (4.5)

Moraxella catarrhalis

-

1 (2.3)

Staphylococcus aureus

-

2 (4.5)

Haemophilus influenza

2 (3.8)

-

Enterobacteriace

4 (7.5)

3 (6.8)

Enterococci

-

1 (2.3)

Escherichia coli

1(1.9)

2 (4.5)

Pseudomonas aeruginosa

-

2 (4.5)

Klebsiella pneumoniae

-

1 (2.3)

Virology positive

  

n (% of patients)

5 (9.4)

12 (27.3)

Rhinovirus

1 (1.9)

-

RSV

-

4 (9.1)

HSV type 1

1 (1.9)

2 (4.5)

HSV type 2

-

1 (2.3)

parainfluenza 1

1 (1.9)

-

parainfluenza 3

1 (1.9)

-

CMV

1 (1.9)

5 (11.4)

Bacteriology and virology positive

1 (1.9)

4 (9.1)

Fungi

  

n (% of patients)

16 (30.2)

23 (52.3)

Aspergillus

7 (13.2)

9 (20.4)

Candida albicans

6 (11.3)

8 (18.1)

Other

3 (5.7)

6 (13.6)

  1. AE-COPD acute exacerbations of COPD, RSV respiratory syncytial virus, HSV herpes simpex virus, CMV cytomegalovirus, n = number of patients