Fig. 7From: Hyperoxia-induced methylation decreases RUNX3 in a newborn rat model of bronchopulmonary dysplasiaBSP detection of DNA methylation in the RUNX3 promoter region of AT2 cells. The detection of 16 sites in the RUNX3 promoter region by BSP demonstrated the DNA methylation percentage of the RUNX3 promoter region in AT2 cells (a). In each specimen, the DNA methylation proportion differed at different sites (b, c). The DNA methylation proportion was higher in AT2 cells of the model group compared to that in the control group (d). Closed circles: methylated CpGs; open circles: unmethylated CpGs. *P < 0.05 vs. control group, n = 7Back to article page