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Fig. 2 | Respiratory Research

Fig. 2

From: Hyperoxia-induced methylation decreases RUNX3 in a newborn rat model of bronchopulmonary dysplasia

Fig. 2

DNMTs and EZH2 protein localization in lung tissues following hyperoxia. DNMTs and EZH2 protein localization in lung tissues by immunohistochemistry. After 10 day of hyperoxia, DNMT1 protein was expressed in pulmonary alveolar epithelial cells in the control group (a), but, in the model group, DNMT1 protein was barely detectable (b). In both the control (c) and model groups (d), DNMT3b protein was expressed in alveolar epithelial and mesenchymal cells. In the control group, EZH2 protein was poorly expressed (e). In the model group, EZH2 protein was expressed in alveolar epithelial cells (f). The arrow points to positive cells. (×400)

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