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Table 1 Identified proteins in control and NSCLC tissues by MS analysis

From: Differentially expressed and activated proteins associated with non small cell lung cancer tissues

Protein

Gene

Gene ID

MWa

Mascot Scoreb

Mascot Scoreb

[Peptide]c

[Peptide]c

NSCLC

Control

lactoferrin precursor

LTF

12083188

80214

946 [15]

298 [5]

transferrin

TF

37747855

79310

581 [9]

940 [15]

78 kDa glucose-regulated protein precursor

HSPA5

16507237

72402

507 [8]

503 [8]

moesin

MSN

4505257

67892

412 [8]

396 [7]

myeloperoxidase, isoform CRA_d

MPO

119614879

76923

331 [6]

73 [1]

protein disulfide-isomerase A4 precursor

PDIA4

4758304

73229

191 [3]

128 [2]

glyceraldehyde-3-phosphate dehydrogenase

GAPDH

31645

36201

581 [9]

375 [6]

annexin A2 isoform 2

ANXA2

18645167

38808

975 [16]

504 [10]

annexin A1

ANXA1

4502101

38918

587 [8]

522 [7]

L-lactate dehydrogenase A isoform 1

LDHA

5031857

36950

391 [7]

N. D.d

aldolase A

ALDOA

28614

39706

240 [4]

65 [1]

peroxiredoxin-1

PRDX1

4505591

22324

158 [3]

253 [5]

Aldo-keto reductase family 1 member C4

AKR1C4

308153631

37442

155 [3]

N. D.d

60S acidic ribosomal protein P0

RPLP0

4506667

34423

133 [2]

N. D.d

Actin, beta

ACTB

16359158

42078

103 [2]

238 [4]

alcohol dehydrogenase beta subunit

ADH1B

178098

40665

N. D.d

107 [2]

cathepsin D

CTSD

157879206

26511

151 [3]

131 [2]

stomatin

STOM

14715077

31958

112 [2]

N. D.d

apolipoprotein A-I, isoform CRA_b

APOA1

177827

23454

566 [9]

1057 [17]

ribosomal protein L7

RPL7

1335288

29907

170 [2]

75 [1]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

YWHAG

380765197

28373

169 [2]

96 [1]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide variant

YWHAB

62089104

22563

48 [1]

113 [2]

triosephosphate isomerase 1

TPI1

136066

26894

633 [10]

394 [6]

proteasome subunit alpha type-6

PSMA6

8394076

27838

184 [3]

65 [1]

carbonic anhydrase 1

CA1

4502517

28909

104 [2]

482 [8]

carbonic anhydrase 2

CA2

15080386

29215

N. D.d

237 [4]

azurocidin

AZU1

28977

27093

130 [2]

N. D.d

phosphoglycerate mutase 1

PGAM1

4505753

28900

91 [2]

N. D.d

enoyl-CoA hydratase

EHHADH

1922287

31807

107 [2]

N. D.d

profilin-1

PFN1

4826898

15216

N. D.d

103 [2]

endoplasmic reticulum protein 29, isoform CRA_b

ERP29

119618398

29638

102 [2]

N. D.d

pre-serum amyloid P component

APCS

337758

25495

337 [5]

318 [5]

peroxiredoxin-6

PRDX6

134254698

25011

342 [6]

299 [5]

MHC class II antigen

HLA-DRB1

10185082

30525

N. D.d

183 [3]

MHC class I antigen

HLA-DQB

325656872

21947

N. D.d

150 [3]

Rab5c-like protein

RAB5C

508285

23781

101 [2]

97 [2]

proteasome subunit beta type-4

PSMB4

22538467

29242

N. D.d

211 [3]

rho GDP-dissociation inhibitor

ARHGDIB

56676393

23031

N. D.d

122 [2]

  1. aTheoretical MW
  2. bProtein score assigned by Mascot software is derived from ion scores that are -10*Log [p], where p is the probability that the observed match is a random event
  3. cNumber of peptides matched
  4. dNot determined