Skip to main content

Table 1 Effects of sakuranetin treatment on cytokine release in lung homogenates as quantified by ELISA (Bio-Plex)

From: A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases

 

SAL+Ve

ELA+Ve

SAL+SK

ELA+SK

M-CSF (pg/mL)

1.08 ± 1.05

10.95 ± 1.36*

1.64 ± 1.37

1.72 ± 1.18**

IL-1β (pg/mL)

0.92 ± 0.18

1.92 ± 0.25*

1.28 ± 0.25

0.82 ± 0.22**

MCP-1 (pg/mL)

5.90 ± 2.32

11.00 ± 2.32

4.73 ± 2.68

8.77 ± 2.32

TNFα (pg/mL)

0.21 ± 0.03

0.33 ± 0.04*

0.15 ± 0.04

0.15 ± 0.03**

MIP-2 (pg/mL)

10.00 ± 1.50

10.24 ± 1.50

7.98 ± 1.93

10.55 ± 1.50

  1. Data are presented as the mean ± SE. SAL+Ve: control group with vehicle treatment; ELA+Ve: elastase instillation and vehicle treatment; SAL+SK: control group treated with sakuranetin; ELA + SK: elastase- and sakuranetin-treated group. *p < 0.05 compared with the SAL groups; **p < 0.01 compared with the ELA+Ve group